⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4534517 | 0.72 | — | — | |
| SCHEMBL1683193 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL1117931 | 0.69 | — | — | |
| SCHEMBL21170262 | 0.69 | — | — | |
| Water SCHEMBL28495542 | 0.69 | — | — | |
| SCHEMBL23798274 | 0.69 | — | — | |
| SCHEMBL15458241 | 0.69 | — | — | |
| SCHEMBL28111980 | 0.67 | — | — | |
| SCHEMBL1100062 | 0.65 | — | — | |
| SCHEMBL29277972 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459003-B | Pyrazole amide derivatives | 帝人制药株式会社 | 2019-06-21 | — | — | CN | disclosed |
| CN-108472284-A | β -lactamase inhibitor | 维纳拓尔斯制药公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-104981160-B | Pesticidal compositions and methods related thereto | 美国陶氏益农公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-107922437-A | Bridging piperidine derivative | 豪夫迈·罗氏有限公司 | 2018-04-17 | — | — | CN | disclosed |
| CN-105008344-B | Bruton's tyrosine kinase inhibitor | 辉瑞公司 | 2017-07-25 | — | — | CN | disclosed |
| CN-106661012-A | Carboxamide derivatives | 诺华股份有限公司 | 2017-05-10 | — | — | CN | disclosed |
| CN-106459003-A | Pyrazole amide derivatives | 帝人制药株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-106459004-A | Pyrazole amide derivative | 研究三角协会 | 2017-02-22 | — | — | CN | disclosed |
| CN-103476771-A | IL17 and IFN-gamma inhibition for the treatment of autoimmune inflammation | 4SC DISCOVERY GMBH | 2013-12-25 | — | — | CN | disclosed |
| CN-103459385-A | IL17 and IFN-[gamma] inhibition for the treatment of autoimmune inflammation | 4SC DISCOVERY GMBH | 2013-12-18 | — | — | CN | disclosed |
| CN-101678007-B | Gonadotropin-releasing hormone receptor antagonists and its pharmaceutical application | NEUROCRINE BIOSCIENCES INC | 2013-07-03 | — | — | CN | disclosed |
| CN-101253155-B | 11-beta-hydroxysteroid dehydrogenase-1-inhibitor-diabetes-type 2-1 | HOFFMANN LA ROCHE | 2011-11-09 | — | — | CN | disclosed |
| CN-102159548-A | Amide compounds useful in therapy | PFIZER LTD | 2011-08-17 | — | — | CN | disclosed |
| CN-102137855-A | Process for preparing certain cinnamide compounds | EISAI R&D MAN CO LTD | 2011-07-27 | — | — | CN | disclosed |
| CN-101175747-B | Substituted N-arylpyrrolidines as selective androgen receptor modulators | LILLY CO ELI | 2011-06-22 | — | — | CN | disclosed |
| CN-102046601-A | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R TECH UENO LTD | 2011-05-04 | — | — | CN | disclosed |
| CN-101678007-A | gonadotropin-releasing hormone receptor antagonists and methods relating thereto | NEUROCRINE BIOSCIENCES INC | 2010-03-24 | — | — | CN | disclosed |
| CN-101253155-A | 11-beta-hydroxysteroid dehydrogenase-1-inhibitor-diabetes-type 2-1 | HOFFMANN LA ROCHE (CH) | 2008-08-27 | — | — | CN | disclosed |
| CN-101175747-A | Substituted N-arylpyrrolidines as selective androgen receptor modulators | LILLY CO ELI (US) | 2008-05-07 | — | — | CN | disclosed |
| CN-1067685-C | Pyridazinoquinoline compounds | ZENECA LTD (GB) | 2001-06-27 | — | — | CN | disclosed |