Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363242 | 0.98 | FFAR1 (0.52) | FFAR1FFAR4PTPN11CYP2C19MEN1 | |
| SCHEMBL13757141 | 0.94 | PTPN11 (0.51) | FFAR1FFAR4PTPN11NPC1ALDH1A1 | |
| SCHEMBL22197977 | 0.87 | PTPN11 (0.46) | FFAR1FFAR4PTPN11NPC1ALDH1A1 | |
| SCHEMBL3007588 | 0.87 | PTPN11 (0.46) | PTPN11CYP2C19MEN1CYP1A2CYP2D6 | |
| SCHEMBL13831561 | 0.84 | FFAR1 (0.45) | FFAR1FFAR4PTPN11MEN1KMT2A | |
| SCHEMBL17996034 | 0.84 | FFAR1 (0.51) | FFAR1FFAR4CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL14715015 | 0.83 | PTPN11 (0.48) | PTPN11NPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3018699 | 0.82 | PTPN11 (0.47) | PTPN11NPC1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL3587230 | 0.81 | FFAR1 (0.43) | FFAR1FFAR4ALDH1A1MAPTHAO1 | |
| SCHEMBL4498928 | 0.80 | FFAR1 (0.60) | FFAR1FFAR4PTPN11KMT2AHAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054624-A1 | MODULATORS OF ALPHA-1 ANTITRYPSIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2024-03-14 | — | — | WO | disclosed |