Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736019 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL1300090 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL18227162 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL27385617 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL1300093 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL16746025 | 1.00 | CCNE1 (0.34) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL561595 | 0.87 | EPHX1 (0.39) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL525096 | 0.87 | EPHX1 (0.35) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL1799225 | 0.85 | EPHX1 (0.42) | CCNE1CDK2GSK3BMMP1MMP9 | |
| SCHEMBL20469204 | 0.84 | CCNE1 (0.38) | CCNE1CDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4424713-A2 | AGENTS FOR CLEAVING LABELS FROM BIOMOLECULES IN VIVO | Tagworks Pharmaceuticals B.V. (NL) | 2024-09-04 | — | — | EP | disclosed |
| WO-2024036096-A2 | TRANSFERRIN RECEPTOR BINDING PROTEINS AND CONJUGATES | ELI LILLY AND COMPANY (US) | 2024-02-15 | — | — | WO | disclosed |
| CN-114599645-A | Reagents for cleaving a label from a biomolecule in vivo | 泰克沃尔科斯制药有限公司 | 2022-06-07 | — | — | CN | disclosed |