SCHEMBL27366138

SCHEMBL27366138

Cc1oc2ncnc(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3)c2c1-c1cccc(N)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MERTK Q12866 20/20 1.00
AXL P30530 19/20 1.00
TYRO3 Q06418 2/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27366132 0.92 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27365616 0.91 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27366137 0.91 MERTK (0.83) MERTKAXLTYRO3
SCHEMBL27365772 0.90 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27365774 0.88 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL31512153 0.88 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27365620 0.88 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27366204 0.88 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27365945 0.88 MERTK (1.00) MERTKAXLTYRO3
SCHEMBL27366542 0.88 MERTK (1.00) MERTKAXLTYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024039842-A2 INHIBITORS OF TAM RECEPTORS NATIONAL HEALTH RESEARCH INSTITUTES (TW) 2024-02-22 WO disclosed