Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.95 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.95 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.95 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | MC4R | P32245 | 1/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.68 |
| ▸ | MC3R | P41968 | 1/20 | 0.68 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrazinoic Acid SCHEMBL9478203 | 1.00 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL28046860 | 1.00 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL29651929 | 0.98 | — | — | |
| Pyrazinoic Acid SCHEMBL23757 | 0.98 | — | — | |
| Pyrazinoic Acid SCHEMBL28292273 | 0.96 | KDM4E (0.87) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL10349317 | 0.95 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL8335237 | 0.95 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL623119 | 0.95 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL6631652 | 0.95 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 | |
| Pyrazinoic Acid SCHEMBL8978502 | 0.95 | KDM4E (0.95) | KDM4ENAPRTHCAR2TSHRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1063180-C | 5H, 10H-imidazo [1, 2 -a] indeno [1, 2 -e] pyrazin-4-one derivatives, preparation thereof, and drugs containing said derivatives | RHONE POULENC RORER SA (FR) | 2001-03-14 | — | — | CN | disclosed |
| CN-1180357-A | 5H, 10H-imidazo [1, 2-a ] indeno [1, 2-e ] pyrazin-4-one derivatives, preparation thereof and medicaments containing same | RHONE POULENC RORER SA (FR) | 1998-04-29 | — | — | CN | disclosed |