Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 5/20 | 0.32 |
| ▸ | HTR1B | P28222 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12161361 | 0.81 | KMT2A (0.35) | IRAK4HTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL14553365 | 0.81 | KMT2A (0.35) | IRAK4HTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL14832425 | 0.81 | KMT2A (0.35) | IRAK4HTR1DHTR1BHTR1AKMT2A | |
| SCHEMBL2365737 | 0.79 | — | — | |
| SCHEMBL1439579 | 0.79 | — | — | |
| SCHEMBL1439581 | 0.79 | — | — | |
| SCHEMBL6962555 | 0.78 | CD274 (0.37) | HTR1DHTR1BS1PR1 | |
| SCHEMBL19692710 | 0.76 | — | — | |
| SCHEMBL2035483 | 0.76 | — | — | |
| SCHEMBL19128284 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061853-A1 | FLUORESCENT PROBES FOR MAGL | F. HOFFMANN-LA ROCHE AG (CH) | 2024-03-28 | — | — | WO | disclosed |