SCHEMBL27368548

SCHEMBL27368548

N#Cc1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5cc(-c6ccccc6)ccc5-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cc4)n3)c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 12/20 0.48
ABCB1 P08183 8/20 0.48
ABCC1 P33527 3/20 0.43
GABRA1 P14867 1/20 0.43
GABRG2 P18507 1/20 0.43
GABRB3 P28472 1/20 0.43
GABRA5 P31644 1/20 0.43
GABRA3 P34903 1/20 0.43
MEN1 O00255 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2C19 P33261 2/20 0.42
KMT2A Q03164 2/20 0.42
CLK4 Q9HAZ1 2/20 0.42
LMNA P02545 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27368445 0.97 ABCG2 (0.46) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL27368459 0.96 ABCG2 (0.45) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL27368555 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL26591991 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL31643063 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL31642854 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL26591988 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL31643519 0.96 ABCG2 (0.49) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL31643465 0.95 ABCG2 (0.46) ABCG2ABCB1ABCC1GABRA1GABRG2
SCHEMBL31643260 0.95 ABCG2 (0.46) ABCG2ABCB1ABCC1GABRA1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400501-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2024-07-17 EP disclosed
WO-2024053991-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-03-14 WO disclosed