SCHEMBL27368720

SCHEMBL27368720

OC(c1ccccc1)(c1cccnc1)c1ccccc1Cl

nearest known ligand 0.86

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.86
CYP3A5 P20815 7/20 0.86
CYP19A1 P11511 9/20 0.61
KCNA5 P22460 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
RORC P51449 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904433 0.92 CYP3A4 (1.00) CYP3A4CYP3A5CYP19A1
SCHEMBL10431413 0.89 CYP3A4 (0.92) CYP3A4CYP3A5CYP19A1
SCHEMBL20323185 0.88 CYP3A4 (0.68) CYP3A4CYP3A5CYP19A1KCNA5CYP1A2
Fenarimol SCHEMBL8408558 0.87 CYP3A4 (0.90) CYP3A4CYP3A5CYP19A1
SCHEMBL27282170 0.85 CYP19A1 (0.82) CYP3A4CYP3A5CYP19A1
SCHEMBL2131459 0.84 CYP3A4 (0.60) CYP3A4CYP3A5CYP19A1CYP1A2CYP2C9
SCHEMBL30114522 0.84 CYP3A4 (0.60) CYP3A4CYP3A5CYP19A1CYP1A2CYP2C9
SCHEMBL913686 0.82 CYP19A1 (0.72) CYP3A4CYP3A5CYP19A1KCNA5CYP1A2
SCHEMBL11629409 0.81 CYP3A4 (0.62) CYP3A4CYP3A5CYP19A1KCNA5CYP1A2
SCHEMBL6369689 0.80 KCNN4 (0.57) CYP3A4CYP3A5CYP19A1CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1104195-C Adjuvant composition for agricutural chemicals and method for enhancing the efficacy of agricultural chemical KAO CORP (JP) 2003-04-02 CN disclosed
CN-1073795-C Agricultural chemical composition KAO CORP (JP) 2001-10-31 CN disclosed
CN-1173110-A Adjuvant composition for agricutural chemicals and method for enhancing the efficacy of agricultural chemical KAO CROP (JP) 1998-02-11 CN disclosed
CN-1111474-A Agricultural chemical composition KAO CORP (JP) 1995-11-15 CN disclosed