Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 8/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8835109 | 0.81 | EGFR (0.61) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9520372 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL11881743 | 0.81 | KDM4E (0.53) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL3259553 | 0.80 | KDM4E (0.64) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL133403 | 0.79 | EGFR (0.64) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL5138495 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL29578942 | 0.79 | GSK3B (0.52) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL1080129 | 0.79 | GSK3B (0.52) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL22033363 | 0.77 | POLB (0.66) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL7940151 | 0.75 | KDM4E (0.67) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | disclosed |