Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 19/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.35 |
| ▸ | NRAS | P01111 | 6/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29748417 | 1.00 | FLT3 (0.39) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL24574063 | 1.00 | FLT3 (0.39) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL31068074 | 0.92 | FLT3 (0.38) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL24574002 | 0.92 | FLT3 (0.38) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL27369776 | 0.92 | FLT3 (0.38) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL24573939 | 0.90 | FLT3 (0.42) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL24976679 | 0.88 | IRAK4 (0.36) | FLT3IRAK4NRAS | |
| SCHEMBL24574348 | 0.88 | FLT3 (0.48) | FLT3IRAK4NRASIRAK1 | |
| SCHEMBL31557818 | 0.88 | IRAK4 (0.36) | FLT3IRAK4NRAS | |
| SCHEMBL24574380 | 0.88 | FLT3 (0.48) | FLT3IRAK4NRASIRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250431-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-12-28 | — | — | WO | disclosed |