Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.76 |
| ▸ | CDK2 | P24941 | 12/20 | 0.65 |
| ▸ | CCNE1 | P24864 | 10/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27370878 | 0.89 | GSK3B (0.72) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL27370456 | 0.87 | GSK3B (0.69) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL13146697 | 0.87 | GSK3B (0.71) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12953029 | 0.87 | GSK3B (1.00) | GSK3BCDK2CCNE1 | |
| SCHEMBL30356813 | 0.85 | GSK3B (0.70) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12953359 | 0.85 | GSK3B (0.69) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12953189 | 0.82 | GSK3B (0.71) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12953181 | 0.81 | GSK3B (0.64) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12954514 | 0.80 | GSK3B (0.61) | GSK3BCDK2CCNE1NPC1RAB9A | |
| SCHEMBL12953734 | 0.79 | GSK3B (0.85) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054953-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |