Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 11/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18598370 | 1.00 | ATM (0.61) | ATMDRD4DRD2LMNAHTT | |
| SCHEMBL7454696 | 0.86 | DRD4 (0.51) | ATMDRD4DRD2LMNAHTT | |
| SCHEMBL26021646 | 0.85 | DRD4 (0.50) | ATMDRD4DRD2LMNAHTT | |
| SCHEMBL18193569 | 0.85 | ATM (0.57) | ATMDRD4LMNAHTTMAPK1 | |
| SCHEMBL18193570 | 0.85 | ATM (0.57) | ATMDRD4LMNAHTTMAPK1 | |
| SCHEMBL18193576 | 0.84 | ATM (0.52) | ATMDRD4DRD2LMNAHTT | |
| SCHEMBL18193568 | 0.84 | ATM (0.52) | ATMDRD4DRD2LMNAHTT | |
| SCHEMBL17233347 | 0.82 | ESR1 (0.47) | ATMDRD4DRD2LMNAMAPK1 | |
| SCHEMBL17233213 | 0.82 | MAPT (0.49) | ATMDRD4LMNAL3MBTL1PPARA | |
| SCHEMBL8459687 | 0.82 | ATM (0.63) | ATMDRD4DRD2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |