Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27317197 | 0.94 | SMN1; SMN2 (0.63) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL27576427 | 0.87 | SMN1; SMN2 (0.63) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL1202914 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL20396247 | 0.81 | SMN1; SMN2 (0.59) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL6832945 | 0.80 | SMN1; SMN2 (0.46) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL8875531 | 0.79 | SMN1; SMN2 (0.82) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL15214262 | 0.79 | SMN1; SMN2 (0.60) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL27287426 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2PKMPOLBTDP1KDM4E | |
| SCHEMBL8593844 | 0.79 | TSHR (0.46) | SMN1; SMN2POLBKDM4ETSHRMAPK1 | |
| SCHEMBL7970186 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2PKMPOLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1064955-C | Fluorine-containing benzoylguanidines | MERCK PATENT GMBH (DE) | 2001-04-25 | — | — | CN | disclosed |
| CN-1143632-A | Fluorine-containing benzoylguanidines | MERCK PATENT GMBH (DE) | 1997-02-26 | — | — | CN | disclosed |