Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CETP | P11597 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 6/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10264464 | 0.98 | CYP4F2 (0.45) | CYP4F2CYP4A11ALDH1A1CETPATM | |
| SCHEMBL27260326 | 0.88 | CYP4F2 (0.53) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL8411261 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL16653040 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL14697097 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL16652987 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL14697386 | 0.86 | CYP4F2 (0.51) | CYP4F2CYP4A11CETPACHENAAA | |
| SCHEMBL28630718 | 0.86 | CYP4F2 (0.46) | CYP4F2CYP4A11ALDH1A1CETPATM | |
| SCHEMBL186860 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1CETPATM | |
| SCHEMBL186379 | 0.85 | CYP4F2 (0.48) | CYP4F2CYP4A11ALDH1A1CETPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402300-B1 | Hydroxyl compounds and compositions for cholesterol management and related uses | ESPERION THERAPEUTICS INC (US) | 2016-05-25 | — | — | EP | disclosed |
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2402300-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-04 | — | — | EP | disclosed |