Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL187263 | 0.82 | — | — | |
| SCHEMBL12309731 | 0.77 | — | — | |
| SCHEMBL9387825 | 0.72 | KMT2A (0.59) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL10472497 | 0.70 | KMT2A (0.59) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL30417213 | 0.70 | KMT2A (0.59) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL10759033 | 0.69 | KMT2A (0.56) | MAPTKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL2736783 | 0.68 | MAPT (0.47) | MAPTKDM4EKMT2AMEN1USP2 | |
| SCHEMBL187075 | 0.67 | — | — | |
| SCHEMBL29008029 | 0.67 | KMT2A (0.53) | MAPTKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL2736543 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402314-A1 | (Aza)indole derivative and use thereof for medical purposes | Kissei Pharmaceutical Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |