Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374013 | 0.87 | SMN1; SMN2 (0.61) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374100 | 0.82 | NPC1 (0.66) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374470 | 0.81 | NPC1 (0.61) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374091 | 0.81 | NPC1 (0.61) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL31503214 | 0.81 | NPC1 (0.61) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374251 | 0.80 | SMN1; SMN2 (0.59) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374265 | 0.80 | NPC1 (0.77) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374095 | 0.79 | NPC1 (0.59) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL27374263 | 0.79 | SMN1; SMN2 (0.79) | NPC1RAB9AGAANFKB1NFKB2 | |
| SCHEMBL10824061 | 0.78 | NPC1 (0.58) | NPC1RAB9AGAANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031002-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2024-02-08 | — | — | WO | disclosed |