Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375825 | 0.85 | TDP1 (0.57) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL27374270 | 0.84 | TDP1 (0.56) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL27374443 | 0.79 | TDP1 (0.57) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL27374367 | 0.74 | TDP1 (0.61) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL27374181 | 0.72 | HPGD (0.69) | SMN1; SMN2MAPTLMNANPC1RAB9A | |
| SCHEMBL22592011 | 0.69 | SMN1; SMN2 (0.47) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL28644024 | 0.67 | TDP1 (0.68) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| 2,4-Dichlorophenoxyacetic Acid, Methyl Ester SCHEMBL5004223 | 0.67 | MAPT (0.70) | TDP1SMN1; SMN2TSHRMAPTLMNA | |
| SCHEMBL6202463 | 0.67 | TDP1 (0.68) | TDP1SMN1; SMN2TSHRMAPTNPC1 | |
| SCHEMBL27374823 | 0.67 | SMN1; SMN2 (0.67) | TDP1SMN1; SMN2TSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031002-A1 | (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS | CORTEVA AGRISCIENCE LLC (US) | 2024-02-08 | — | — | WO | disclosed |