Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372927 | 0.88 | GRM5 (0.38) | GRM5MAOB | |
| SCHEMBL27372858 | 0.88 | GRM5 (0.46) | GRM5CHKAMAOB | |
| SCHEMBL27375256 | 0.85 | MAOB (0.31) | MAOB | |
| SCHEMBL31573916 | 0.78 | GRM5 (0.43) | GRM5 | |
| SCHEMBL27373016 | 0.78 | GRM5 (0.43) | GRM5 | |
| SCHEMBL27376475 | 0.78 | GRM5 (0.43) | GRM5 | |
| SCHEMBL27375264 | 0.78 | MAOB (0.35) | MAOB | |
| SCHEMBL27375259 | 0.77 | GRM5 (0.38) | GRM5MAOB | |
| SCHEMBL31573915 | 0.77 | GRM5 (0.50) | GRM5 | |
| SCHEMBL27374459 | 0.77 | GRM5 (0.50) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024068948-A1 | NOVEL COMPOUNDS FOR THE DIAGNOSIS OF TDP-43 PROTEINOPATHIES | AC IMMUNE SA (CH) | 2024-04-04 | — | — | WO | disclosed |