Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 4/20 | 0.38 |
| ▸ | CDK2 | P24941 | 4/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | PNP | P00491 | 2/20 | 0.38 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HBB | P68871 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374373 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL18458052 | 0.88 | ADORA2A (0.52) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL27374918 | 0.86 | CDK1 (0.40) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL16769795 | 0.84 | CDK2 (0.54) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL22381492 | 0.83 | CDK1 (0.42) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL27375754 | 0.80 | CDK1 (0.39) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL27374408 | 0.78 | HPRT1 (0.40) | ADORA2AADORA2BADORA1CDK1CDK2 | |
| SCHEMBL27374409 | 0.74 | GAA (0.38) | CDK1CDK2CCNB1CCNE1HPRT1 | |
| SCHEMBL10048814 | 0.74 | BLM (0.38) | CDK1CDK2CCNB1CCNE1PNP | |
| SCHEMBL27374338 | 0.74 | HPRT1 (0.39) | CDK1CDK2CCNB1CCNE1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015941-A2 | DINUCLEOTIDES AND THEIR USE IN TREATING CANCER | MAIA BIOTECHNOLOGY, INC. (US) | 2024-01-18 | — | — | WO | disclosed |