Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | PNP | P00491 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375503 | 1.00 | POLB (0.46) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL27375716 | 1.00 | POLB (0.46) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL10015785 | 1.00 | POLB (0.46) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL27374453 | 0.87 | PNP (0.52) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL27374375 | 0.87 | PNP (0.52) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL26294898 | 0.87 | PNP (0.52) | POLBPDE3APNPLMNATP53 | |
| SCHEMBL13252942 | 0.86 | POLB (0.59) | POLBPDE3APNPSTING1PDE3B | |
| SCHEMBL10015775 | 0.86 | POLB (0.59) | POLBPDE3APNPSTING1PDE3B | |
| SCHEMBL6914307 | 0.86 | POLB (0.59) | POLBPDE3APNPSTING1PDE3B | |
| Ateganosine SCHEMBL531274 | 0.85 | PNP (0.64) | POLBPDE3APNPLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015941-A2 | DINUCLEOTIDES AND THEIR USE IN TREATING CANCER | MAIA BIOTECHNOLOGY, INC. (US) | 2024-01-18 | — | — | WO | disclosed |