Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.41 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3660482 | 1.00 | CHRM5 (0.52) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| SCHEMBL14505993 | 1.00 | CHRM5 (0.52) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| SCHEMBL29862023 | 0.98 | CHRM5 (0.56) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL20520976 | 0.98 | CHRM5 (0.50) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL8449332 | 0.98 | CHRM5 (0.50) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| SCHEMBL2462435 | 0.98 | CHRM5 (0.56) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| SCHEMBL13950187 | 0.98 | CHRM5 (0.56) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL20520975 | 0.98 | CHRM5 (0.50) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| Hydrochloric Acid SCHEMBL29134438 | 0.98 | CHRM5 (0.50) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 | |
| SCHEMBL28249891 | 0.98 | CHRM5 (0.56) | CHRM5ADRA2CSLC6A1GABRA5GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045040-A1 | NITROGEN CONTAINING BICYCLIC COMPOUNDS | Wockhardt Limited (IN) | 2022-08-24 | — | — | EP | disclosed |
| CN-102971291-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2015-07-22 | — | — | CN | disclosed |
| CN-101437819-B | Pyridopyrazines and derivatives thereof as alk and c-MET inhibitors | CEPHALON INC | 2013-06-19 | — | — | CN | disclosed |
| CN-102971291-A | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2013-03-13 | — | — | CN | disclosed |
| CN-101456841-B | Amide derivative and medicine | NIPPON SHINYAKU CO LTD | 2012-01-25 | — | — | CN | disclosed |
| CN-100526298-C | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2009-08-12 | — | — | CN | disclosed |
| CN-101456841-A | Amide derivative and medicine | NIPPON SHINYAKU CO LTD (JP) | 2009-06-17 | — | — | CN | disclosed |
| CN-101437819-A | Pyridopyrazines and derivatives thereof as ALK and c-MET inhibitors | CEPHALON INC (US) | 2009-05-20 | — | — | CN | disclosed |
| CN-1898208-A | Amide derivative and pharmaceutical | NIPPON SHINYAKU CO LTD (JP) | 2007-01-17 | — | — | CN | disclosed |
| CN-1041087-C | Arylacetamides | MERCK PATENT AG (DE) | 1998-12-09 | — | — | CN | disclosed |