Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 4/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | YAP1 | P46937 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376807 | 1.00 | ABCB1 (0.40) | ABCB1KLK7GPR119STSSYK | |
| SCHEMBL29968185 | 0.92 | ABCB1 (0.40) | ABCB1KLK7STSPDE4B | |
| SCHEMBL27223326 | 0.91 | ABCB1 (0.40) | ABCB1KLK7GPR119STSSYK | |
| SCHEMBL27376812 | 0.91 | ABCB1 (0.40) | ABCB1KLK7GPR119STSSYK | |
| SCHEMBL30821174 | 0.85 | ABCB1 (0.41) | ABCB1KLK7GPR119STSPDE4B | |
| SCHEMBL24622152 | 0.81 | ABCB1 (0.41) | ABCB1KLK7GPR119STSBACE1 | |
| SCHEMBL21996508 | 0.81 | ABCB1 (0.41) | ABCB1KLK7GPR119STSBACE1 | |
| SCHEMBL22047128 | 0.81 | ABCB1 (0.41) | ABCB1KLK7STSBACE1BACE2 | |
| SCHEMBL5151803 | 0.81 | ABCB1 (0.41) | ABCB1KLK7GPR119STSBACE1 | |
| SCHEMBL28578227 | 0.81 | TACR1 (0.35) | ABCB1KLK7STSKLK5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059806-A1 | BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-03-21 | — | — | WO | disclosed |