Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.51 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AOC2 | O75106 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7332325 | 0.82 | FFAR1 (0.58) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL12659858 | 0.80 | ESR1 (0.56) | SLC5A1SLC5A2HPGDTAAR1LMNA | |
| SCHEMBL27383213 | 0.80 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL9327509 | 0.80 | FFAR1 (0.56) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL193318 | 0.80 | FFAR1 (0.79) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL27482057 | 0.80 | FFAR1 (0.56) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL2486792 | 0.78 | FFAR1 (0.55) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| Hydrochloric Acid SCHEMBL29184696 | 0.78 | FFAR1 (0.76) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| SCHEMBL11260867 | 0.78 | FFAR1 (0.55) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 | |
| Hydrochloric Acid SCHEMBL28568409 | 0.78 | FFAR1 (0.76) | FFAR1SLC5A1SLC5A2PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024050825-A1 | COMPOUNDS AS MLKL INHIBITORS | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2024-03-14 | — | — | WO | disclosed |