SCHEMBL27387014

SCHEMBL27387014

NC1(N)CCCCC1(C(=O)O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.39
CYP2C19 P33261 5/20 0.34
CYP1A2 P05177 4/20 0.32
TSHR P16473 3/20 0.32
ALDH1A1 P00352 3/20 0.32
LMNA P02545 2/20 0.32
AKR1C1 Q04828 1/20 0.32
USP2 O75604 1/20 0.32
BLM P54132 1/20 0.32
CACNA2D1 P54289 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
FFAR3 O14843 1/20 0.32
GRM4 Q14833 6/20 0.31
GRM2 Q14416 2/20 0.31
GRM3 Q14832 2/20 0.31
ALOX15 P16050 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
GRM8 O00222 2/20 0.31
GRM6 O15303 2/20 0.31
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28254635 0.95 NSD2 (0.39) NSD2CYP2C19CYP1A2TSHRALDH1A1
SCHEMBL7217948 0.84 NSD2 (0.39) NSD2CYP2C19CYP1A2TSHRALDH1A1
SCHEMBL4753952 0.83 NSD2 (0.42) NSD2CYP2C19CYP1A2TSHRALDH1A1
SCHEMBL27709210 0.81 NSD2 (0.40) NSD2CYP2C19CYP1A2TSHRALDH1A1
Hydrochloric Acid SCHEMBL4461485 0.80 CYP2C19 (0.42) CYP2C19CYP1A2TSHRALDH1A1LMNA
Hydrochloric Acid SCHEMBL28338549 0.80 CYP2C19 (0.42) CYP2C19CYP1A2TSHRALDH1A1LMNA
SCHEMBL208167 0.80 CYP2C19 (0.42) CYP2C19CYP1A2TSHRALDH1A1LMNA
SCHEMBL7159924 0.78 NSD2 (0.34) NSD2
Ammonia Solution, Strong SCHEMBL9108711 0.77 CYP2C19 (0.40) CYP2C19CYP1A2TSHRALDH1A1LMNA
SCHEMBL10749636 0.77 CYP2C19 (0.46) CYP2C19CYP1A2TSHRALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1191067-C Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2005-03-02 CN claimed
CN-1422619-A Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2003-06-11 CN claimed
CN-1096263-C Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2002-12-18 CN claimed
CN-1264295-A Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2000-08-23 CN claimed
CN-108884119-A Preparation method of bis-dicarboxylic diammineplatinum (II) derivative 昆明贵研药业有限公司 2018-11-23 CN disclosed
CN-1191067-C Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2005-03-02 CN disclosed
CN-1422619-A Lipid composition of high non-soluble platinum matches and lipid body PAMACIA & UPJOHN CO (US) 2003-06-11 CN disclosed
CN-1096263-C Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2002-12-18 CN disclosed
CN-1264295-A Lipid complexes and liposomes of highly insoluble platinum complexes UPJOHN CO (US) 2000-08-23 CN disclosed