Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.66 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738882 | 0.90 | CHRM2 (0.70) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| SCHEMBL2738885 | 0.89 | CHRM2 (0.63) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| SCHEMBL2738884 | 0.88 | CHRM2 (0.69) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| SCHEMBL2738886 | 0.84 | CHRM2 (0.62) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| SCHEMBL218921 | 0.82 | CHRM2 (0.66) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| SCHEMBL2738810 | 0.81 | CHRM2 (0.46) | CHRM2BLMCYP2D6SLC22A1OPRK1 | |
| Doxylamine SCHEMBL12959067 | 0.80 | CHRM2 (1.00) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| Doxylamine SCHEMBL30702275 | 0.80 | CHRM2 (1.00) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| Doxylamine SCHEMBL4709 | 0.80 | CHRM2 (1.00) | CHRM2BLMCYP2D6HDAC6SLC22A2 | |
| Doxylamine SCHEMBL30116312 | 0.80 | CHRM2 (1.00) | CHRM2BLMCYP2D6HDAC6SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |