Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 11/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MLNR | O43193 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738890 | 0.89 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL2738889 | 0.88 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL2738893 | 0.87 | SLC6A4 (0.51) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL2738891 | 0.83 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL218912 | 0.81 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL13689324 | 0.80 | SLC6A2 (0.67) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| Phosphoric Acid SCHEMBL1535335 | 0.79 | CACNA2D1 (0.67) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL4193970 | 0.76 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| Phosphoric Acid SCHEMBL4452410 | 0.75 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 | |
| SCHEMBL2110019 | 0.74 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |