Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CLK2 | P49760 | 1/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TOP1 | P11387 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2738952 | 0.93 | KDM4E (0.65) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL2738945 | 0.92 | KDM4E (0.69) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL2738948 | 0.90 | KDM4E (0.71) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL2738950 | 0.88 | KDM4E (0.70) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL219219 | 0.85 | KDM4E (0.61) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL29351326 | 0.85 | KDM4E (0.75) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL6832069 | 0.85 | KDM4E (0.75) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL219386 | 0.85 | KDM4E (0.66) | KDM4EHPGDALDH1A1LMNATDP1 | |
| Hydrochloric Acid SCHEMBL9773650 | 0.84 | KDM4E (0.74) | KDM4EHPGDALDH1A1LMNATDP1 | |
| SCHEMBL30564254 | 0.82 | KDM4E (0.81) | KDM4EHPGDALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |
| US-8088918-B2 | Noncardiotoxic pharmaceutical compounds | WILLIAMSBURG HOLDINGS LLC (US) | 2012-01-03 | — | — | US | disclosed |