Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | GNAI3 | P08754 | 7/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 7/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 7/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL27463252 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Nonane SCHEMBL27394311 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Tetradecane SCHEMBL27500186 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Octane SCHEMBL11308877 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Decane SCHEMBL28285911 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Heptane SCHEMBL27336545 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Nonane SCHEMBL10873465 | 1.00 | TSHR (0.57) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Heptane SCHEMBL27839638 | 0.97 | TSHR (0.53) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Heptane SCHEMBL28830202 | 0.96 | TSHR (0.61) | TSHRTHRBGNAI3GNAO1GNAI1 | |
| Piperazine SCHEMBL27708668 | 0.96 | TSHR (0.50) | TSHRTHRBGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1997671-A | Peptide Purification by Hard Metal Ion Affinity Chromatography | NOVO NORDISK AS (DK) | 2007-07-11 | — | — | CN | claimed |
| CN-1222147-A | Process for preparation of tetraazamacrocycles | BRACCO SPA (IT) | 1999-07-07 | — | — | CN | claimed |
| CN-105073144-A | Process for producing a complex of a lanthanide with a macrocyclic ligand | AGFA HEALTHCARE NV | 2015-11-18 | — | — | CN | disclosed |
| CN-1997671-B | Peptide Purification by Hard Metal Ion Affinity Chromatography | NOVO NORDISK AS | 2012-07-18 | — | — | CN | disclosed |
| CN-101516899-A | Compositions and methods for cellular imaging and therapy | UNIV TEXAS (US) | 2009-08-26 | — | — | CN | disclosed |
| CN-1997671-A | Peptide Purification by Hard Metal Ion Affinity Chromatography | NOVO NORDISK AS (DK) | 2007-07-11 | — | — | CN | disclosed |
| CN-1083442-C | Process for prepn. of tetraazamacrocycles | BRACCO SPA (IT) | 2002-04-24 | — | — | CN | disclosed |
| CN-1222147-A | Process for preparation of tetraazamacrocycles | BRACCO SPA (IT) | 1999-07-07 | — | — | CN | disclosed |