Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKMYT1 | Q99640 | 19/20 | 0.48 |
| ▸ | WEE1 | P30291 | 4/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | FGR | P09769 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.40 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.40 |
| ▸ | ABL2 | P42684 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
| ▸ | EPHB1 | P54762 | 1/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399345 | 0.91 | PKMYT1 (0.47) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL30905518 | 0.84 | PKMYT1 (0.53) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27397994 | 0.84 | PKMYT1 (0.53) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27398056 | 0.84 | PKMYT1 (0.50) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL30905487 | 0.84 | PKMYT1 (0.50) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27398537 | 0.84 | PKMYT1 (0.40) | PKMYT1WEE1PARP1CDK1 | |
| SCHEMBL30905507 | 0.79 | PKMYT1 (0.43) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27398085 | 0.79 | PKMYT1 (0.43) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL27398836 | 0.78 | PKMYT1 (0.49) | PKMYT1WEE1LCKLYNHCK | |
| SCHEMBL30905599 | 0.78 | PKMYT1 (0.54) | PKMYT1WEE1LCKLYNHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024112853-A1 | COMPOUNDS THAT INHIBIT PKMYT1 | EXELIXIS, INC. (US) | 2024-05-30 | — | — | WO | disclosed |