Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL27504806 | 0.86 | TSHR (0.52) | TSHRLMNASMN1; SMN2MAPTCES1 | |
| SCHEMBL27947172 | 0.85 | ELANE (0.47) | TSHRELANELMNASMN1; SMN2MAPT | |
| Methyl Benzoate SCHEMBL7114932 | 0.85 | TSHR (0.73) | TSHRELANELMNASMN1; SMN2MAPT | |
| Benzamide SCHEMBL28308326 | 0.83 | PARP1 (0.59) | TSHRELANESMN1; SMN2MAPTCES1 | |
| Biphenyl SCHEMBL11806686 | 0.82 | SMN1; SMN2 (0.53) | TSHRELANELMNASMN1; SMN2MAPT | |
| Acetophenone SCHEMBL21177918 | 0.81 | SMN1; SMN2 (0.58) | TSHRLMNASMN1; SMN2MAPTCES1 | |
| Acetophenone SCHEMBL28520094 | 0.81 | TSHR (0.60) | TSHRLMNASMN1; SMN2MAPTCES1 | |
| Acetophenone SCHEMBL27873649 | 0.81 | TSHR (0.60) | TSHRELANELMNASMN1; SMN2MAPT | |
| Acetophenone SCHEMBL27464172 | 0.81 | MAPT (0.62) | TSHRELANELMNASMN1; SMN2MAPT | |
| Benzene SCHEMBL27929884 | 0.81 | TSHR (0.50) | TSHRELANELMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071423-A | BICYCLIC CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1993-04-28 | — | — | CN | disclosed |