SCHEMBL27401164

SCHEMBL27401164

C=CC(=O)N1CC(F)(/C=C\c2cc(C(F)(F)F)on2)C1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CNR1 P21554 2/20 0.33
▸ CNR2 P34972 2/20 0.33
▸ BTK Q06187 4/20 0.33
▸ SLC6A9 P48067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27399259 1.00 CNR1 (0.33) CNR1CNR2BTKSLC6A9
SCHEMBL30835916 0.87 CNR1 (0.32) CNR1CNR2BTKSLC6A9
SCHEMBL27399138 0.87 CNR1 (0.32) CNR1CNR2BTKSLC6A9
SCHEMBL27399261 0.87 — —
SCHEMBL30835929 0.84 CNR1 (0.31) CNR1CNR2BTK
SCHEMBL27399663 0.84 CNR1 (0.31) CNR1CNR2BTK
SCHEMBL27402059 0.80 BTK (0.38) CNR1CNR2BTKSLC6A9
SCHEMBL27402008 0.80 BTK (0.38) CNR1CNR2BTKSLC6A9
SCHEMBL27399493 0.78 BTK (0.33) CNR1CNR2BTKSLC6A9
SCHEMBL27399490 0.78 BTK (0.33) CNR1CNR2BTKSLC6A9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4587424-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS Bridgene Biosciences, Inc. (US) 2025-07-23 — — EP disclosed
CN-119894866-A YAP/TAZ-TEAD oncoprotein inhibitors 布里奇恩生物科学公司 2025-04-25 — — CN disclosed
WO-2024059317-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS BRIDGENE BIOSCIENCES, INC. (US) 2024-03-21 — — WO disclosed
WO-2024059317-A1 YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS BRIDGENE BIOSCIENCES, INC. (US) 2024-03-21 — — WO disclosed
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