Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 5/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2739541 | 1.00 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL2739540 | 1.00 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL2739567 | 1.00 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL2739566 | 1.00 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL12966380 | 0.96 | MME (0.44) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL23030200 | 0.83 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL29531322 | 0.83 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL21748461 | 0.83 | MME (0.56) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL30781147 | 0.83 | MME (0.47) | MMEACECPA1ACE2DPP4 | |
| SCHEMBL5841680 | 0.83 | MME (0.47) | MMEACECPA1ACE2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863832-B1 | AGE INHIBITORS | CENTRE NAT RECH SCIENT (FR) | 2012-01-04 | — | — | EP | disclosed |
| EP-0984959-A4 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO CO (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0984959-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998039326-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |
| US-4923965-A | MICROBIOCIDES, FUNGICIDES | POLITECHNIKA GDANSKA (PL) | 1990-05-08 | — | — | US | disclosed |