Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 6/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17172978 | 0.81 | CYP2C9 (0.42) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL15447123 | 0.79 | CYP2D6 (0.60) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL24607014 | 0.79 | TSHR (0.44) | ALDH1A1TSHR | |
| SCHEMBL15014465 | 0.77 | CYP2C9 (0.42) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL9880274 | 0.75 | SMN1; SMN2 (0.46) | CYP1A2ALDH1A1CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL13515908 | 0.75 | USP2 (0.43) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL23019549 | 0.72 | CYP2C9 (0.39) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL24606655 | 0.71 | MAPT (0.38) | ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL14671038 | 0.71 | CYP2C9 (0.47) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 | |
| SCHEMBL17173175 | 0.71 | CYP2C9 (0.50) | CYP2D6CYP2C9CYP1A2ALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240208941-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS | TYRA BIOSCIENCES, INC. | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208941-A1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS | FGFR1, FGFR2, FGFR3 | CYP2D6 3063/4885CYP2C9 2177/4885CYP1A2 2056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.