Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 6/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | MDM4 | O15151 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311876 | 0.97 | TLR2 (0.61) | TLR2MDM2 | |
| SCHEMBL15715832 | 0.89 | TLR2 (0.63) | TLR2MDM2MDM4TP53 | |
| SCHEMBL20833861 | 0.89 | TLR2 (0.63) | TLR2MDM2MDM4TP53 | |
| SCHEMBL16296628 | 0.88 | MDM4 (0.48) | TLR2MDM2MDM4TP53 | |
| SCHEMBL7420121 | 0.88 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL1000115 | 0.88 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL15203241 | 0.88 | TLR2 (0.54) | TLR2MDM2MDM4TP53 | |
| SCHEMBL1044856 | 0.88 | TLR2 (0.62) | TLR2MDM2MDM4TP53 | |
| SCHEMBL9654639 | 0.88 | TLR2 (0.54) | TLR2MDM2MDM4TP53 | |
| SCHEMBL29367120 | 0.88 | TLR2 (0.62) | TLR2MDM2MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618952-A2 | METHODS FOR TREATING OBESITY WITH AN MC4R AGONIST | Rhythm Pharmaceuticals, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |
| WO-2024108198-A2 | METHODS OF TREATING OBESITY WITH AN MC4R AGONIST | RHYTHM PHARMACEUTICALS, INC. (US) | 2024-05-23 | — | — | WO | disclosed |