Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16464561 | 0.67 | TLR7 (0.47) | TLR7TLR8TSHR | |
| SCHEMBL1801769 | 0.66 | GAA (0.33) | — | |
| Hydrochloric Acid SCHEMBL31714576 | 0.64 | TSHR (0.36) | TLR7TLR8GRM4TSHRCCR4 | |
| SCHEMBL6288971 | 0.64 | MAPT (0.41) | TLR8TSHR | |
| SCHEMBL1805254 | 0.64 | GAA (0.36) | — | |
| SCHEMBL16482236 | 0.64 | TLR8 (0.44) | TLR7TLR8TSHR | |
| SCHEMBL21640750 | 0.62 | PLAU (0.34) | TSHR | |
| SCHEMBL5765140 | 0.62 | TLR7 (0.36) | TLR7TLR8TSHR | |
| SCHEMBL16462614 | 0.61 | TSHR (0.42) | TLR7TLR8TSHR | |
| SCHEMBL5420273 | 0.60 | LRRK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045783-A | Diaza class anti-allergy medicament | PFIZER (US) | 1990-10-03 | — | — | CN | disclosed |