Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | AGER | Q15109 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27819063 | 0.97 | KDM4E (0.51) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL3547214 | 0.91 | KDM4E (0.53) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL6505283 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL17503606 | 0.85 | KDM4E (0.43) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL30292490 | 0.84 | PDE10A (0.47) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL2246378 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL14862302 | 0.83 | HCRTR1 (0.45) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL16537946 | 0.83 | KDM4E (0.42) | KDM4EALDH1A1GAAL3MBTL1PTGDR2 | |
| SCHEMBL30292537 | 0.83 | KDM4E (0.45) | KDM4EALDH1A1GAAL3MBTL1MAPT | |
| SCHEMBL16394404 | 0.80 | HCRTR1 (0.44) | KDM4EALDH1A1GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107145-A | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| CN-1107144-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |