Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19916024 | 0.92 | ESR1 (0.41) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL4890514 | 0.83 | ESR1 (0.43) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL5625 | 0.83 | — | — | |
| SCHEMBL5461 | 0.83 | — | — | |
| SCHEMBL2936955 | 0.83 | ESR2 (0.46) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL881445 | 0.82 | — | — | |
| SCHEMBL10341459 | 0.80 | — | — | |
| Cyclohexane SCHEMBL7799464 | 0.80 | ESR1 (0.40) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL1906708 | 0.80 | ESR1 (0.40) | ESR1ESR2CYP3A4CYP2C9CYP2D6 | |
| SCHEMBL22289146 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119117-A1 | MODIFIED 5' CAP FOR MRNA AND METHODS OF USE THEREOF | PRIME MEDICINE, INC. (US) | 2024-06-06 | — | — | WO | disclosed |