Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSSK1B | Q9BXA7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537370 | 0.97 | POLB (0.36) | POLBTDP1TSSK1BKMT2AMEN1 | |
| SCHEMBL27412965 | 0.96 | POLB (0.35) | POLBTDP1TSSK1BKMT2AMEN1 | |
| SCHEMBL27534461 | 0.96 | POLB (0.35) | POLBTDP1TSSK1BKMT2AMEN1 | |
| SCHEMBL27407951 | 0.94 | POLB (0.43) | POLBTDP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27394329 | 0.84 | KMT2A (0.32) | KMT2A | |
| SCHEMBL27407940 | 0.83 | CNR1 (0.39) | TDP1CNR1ALDH1A1TP53NPSR1 | |
| SCHEMBL27462484 | 0.81 | HDAC1 (0.35) | TDP1SMN1; SMN2CNR1NPSR1 | |
| SCHEMBL27414196 | 0.81 | TDP1 (0.33) | TDP1SMN1; SMN2ITGA4CNR1ALDH1A1 | |
| SCHEMBL27397435 | 0.79 | ANXA2 (0.33) | — | |
| SCHEMBL27421125 | 0.79 | KMT2A (0.32) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1093535-C | Imidazole derivative | SHIONOGI & CO (JP) | 2002-10-30 | — | — | CN | disclosed |
| CN-1158609-A | Imidazole derivative | SHIONOGI & CO (JP) | 1997-09-03 | — | — | CN | disclosed |