⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879759 | 0.78 | — | — | |
| SCHEMBL11873606 | 0.76 | — | — | |
| SCHEMBL1004160 | 0.67 | — | — | |
| SCHEMBL19224019 | 0.63 | — | — | |
| SCHEMBL313460 | 0.60 | — | — | |
| SCHEMBL8392822 | 0.60 | — | — | |
| SCHEMBL18330486 | 0.60 | — | — | |
| SCHEMBL31174817 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL11751862 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL28729360 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015864-A1 | CBL-B INHIBITORS AND ANTI-PD1/ANTI-PD-L1 FOR USE IN THE TREATMENT OF CANCER | HOTSPOT THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |