SCHEMBL274157

SCHEMBL274157

CCN(CC)CCN(C)Cc1cccc(C(=O)Nc2ccc(N3CCCC3)cc2C(=O)N/N=C/c2ccc(Cl)c(C(F)(F)F)c2)c1

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC34A2 O95436 12/20 0.56
SLC34A1 Q06495 1/20 0.39
SLC34A3 Q8N130 1/20 0.39
SLC20A1 Q8WUM9 1/20 0.39
ALDH1A1 P00352 2/20 0.37
HDAC1 Q13547 1/20 0.35
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
GFER P55789 1/20 0.34
ADCYAP1R1 P41586 1/20 0.34
RAF1 P04049 1/20 0.34
HIF1A Q16665 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL267818 1.00 SLC34A2 (0.56) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL267819 1.00 SLC34A2 (0.56) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL266052 0.99 SLC34A2 (0.56) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL274630 0.99 SLC34A2 (0.56) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL266053 0.99 SLC34A2 (0.56) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL274349 0.96 SLC34A2 (0.55) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL265846 0.96 SLC34A2 (0.55) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL265845 0.96 SLC34A2 (0.55) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL274037 0.95 SLC34A2 (0.52) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1
SCHEMBL265714 0.95 SLC34A2 (0.52) SLC34A2SLC34A1SLC34A3SLC20A1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed
US-8134015-B2 Compound inhibiting in vivo phosphorous transport and medicine containing the same KYOWA HAKKO KIRIN CO., LTD. (JP) 2012-03-13 US disclosed