SCHEMBL27416993

SCHEMBL27416993

CCCCCCCC(F)Cl

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.48
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
ALDH1A1 P00352 1/20 0.41
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
CES2 O00748 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL527454 1.00 MAPT (0.48) MAPTTSHRTHRBLMNADNM1
SCHEMBL8675733 0.97
Trimethylammonium SCHEMBL605911 0.90 MAPT (0.40) MAPTTSHRTHRBLMNADNM1
SCHEMBL1399751 0.88
SCHEMBL24926247 0.77 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
Heptane SCHEMBL15226631 0.77 TSHR (0.50) MAPTTSHRTHRBLMNADNM1
SCHEMBL2892345 0.77 TSHR (0.50) MAPTTSHRTHRBLMNADNM1
SCHEMBL45648 0.77 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL3362398 0.77 MAPT (0.52) MAPTTSHRTHRBLMNADNM1
SCHEMBL19853017 0.77 MAPT (0.52) MAPTTSHRTHRBLMNADNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1169520-C Porous microparticles and methods of use thereof �Ϳ���ҽҩ��˾ 2004-10-06 CN disclosed
CN-1085700-C random copolymer composition SHELL OIL CO (US) 2002-05-29 CN disclosed
CN-1272058-A Perforated microparticles and methods of use INHALE THERAPEUTIC SYSTEMS CO (US) 2000-11-01 CN disclosed
CN-1147827-A Random copolymer compositions SHELL OIL CO (US) 1997-04-16 CN disclosed