Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.99 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.99 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.46 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sparsentan SCHEMBL535109 | 0.99 | EDNRA (1.00) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| Sparsentan SCHEMBL29706489 | 0.99 | EDNRA (1.00) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL26867622 | 0.98 | EDNRA (0.97) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL6540396 | 0.95 | EDNRA (0.91) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL7546311 | 0.95 | EDNRA (0.91) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL26867624 | 0.94 | EDNRA (0.90) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL25084441 | 0.94 | EDNRA (0.88) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL26867623 | 0.94 | EDNRA (0.89) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL26877305 | 0.94 | EDNRA (0.89) | EDNRAAGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL27423574 | 0.94 | EDNRA (0.87) | EDNRAAGTR1AGTR2ACHELTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393920-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |