Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.55 |
| ▸ | CDK1 | P06493 | 1/20 | 0.55 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.55 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | VDR | P11473 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10067341 | 0.82 | CCNB2 (0.63) | CCNB2CDK1CCNB1CCNB3CYP11B1 | |
| SCHEMBL16454837 | 0.82 | F2 (0.56) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL27549070 | 0.82 | CYP11B1 (0.57) | KIF11CYP11B1CYP11B2AHRF2 | |
| SCHEMBL1260425 | 0.81 | CYP11B1 (0.66) | CYP11B1CYP11B2AHRF2ESR1 | |
| SCHEMBL27568891 | 0.79 | CYP11B1 (0.48) | CCNB2CDK1CCNB1CCNB3CYP11B1 | |
| SCHEMBL5306250 | 0.79 | CYP11B1 (0.54) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL695242 | 0.79 | MAPK14 (0.55) | CYP11B1CYP11B2AHRMAPK14MAPT | |
| SCHEMBL9775886 | 0.79 | ESR1 (0.66) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL29556390 | 0.79 | ESR1 (0.66) | CCNB2CDK1CCNB1CCNB3KIF11 | |
| SCHEMBL15331960 | 0.78 | CCNB2 (0.50) | CCNB2CDK1CCNB1CCNB3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1106383-C | Estrogenic agents | AMERICAN HOME PROD (US) | 2003-04-23 | — | — | CN | disclosed |
| CN-1170719-A | Estrogenic agents | AMERICAN HOME PROD (US) | 1998-01-21 | — | — | CN | disclosed |