Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30750647 | 0.87 | HPGD (0.47) | NR1H2USP2SMN1; SMN2MAPTHPGD | |
| SCHEMBL24032960 | 0.84 | NR1H2 (0.51) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL28890820 | 0.84 | NR1H2 (0.63) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL24033323 | 0.83 | NR1H2 (0.50) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL121357 | 0.83 | NR1H2 (0.54) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL23361270 | 0.82 | NR1H2 (0.52) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL20516045 | 0.81 | NR1H2 (0.53) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL2459787 | 0.81 | NR1H2 (0.51) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL25338213 | 0.79 | NR1H2 (0.49) | NR1H2NAMPTUSP2SMN1; SMN2MAPT | |
| SCHEMBL18497398 | 0.79 | USP2 (0.59) | NR1H2NAMPTUSP2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4637748-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Merck Sharp & Dohme LLC (US) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024137502-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | WO | disclosed |
| WO-2024137502-A2 | PNU ANTHRACYCLINE-DERIVED LINKER-PAYLOADS, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2024-06-27 | — | — | WO | disclosed |