Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27395504 | 0.99 | TACR1 (0.43) | TACR1NR3C1CYP19A1HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9434710 | 0.88 | HTT (0.37) | TACR1DRD2LMNA | |
| Hydrochloric Acid SCHEMBL9434725 | 0.88 | HTT (0.37) | TACR1DRD2LMNA | |
| Hydrochloric Acid SCHEMBL9434721 | 0.88 | HTT (0.37) | TACR1DRD2LMNA | |
| SCHEMBL27396943 | 0.88 | TACR1 (0.44) | TACR1NR3C1HTR1AFFAR2DRD2 | |
| SCHEMBL27395498 | 0.88 | TACR1 (0.44) | TACR1NR3C1CYP19A1HTR1AHTR1D | |
| Hydrochloric Acid SCHEMBL9119259 | 0.87 | TACR1 (0.43) | TACR1NR3C1HTR1AFFAR2DRD2 | |
| Hydrochloric Acid SCHEMBL27534905 | 0.87 | TACR1 (0.43) | TACR1NR3C1HTR1AFFAR2DRD2 | |
| Hydrochloric Acid SCHEMBL9119263 | 0.87 | TACR1 (0.43) | TACR1NR3C1HTR1AFFAR2DRD2 | |
| Hydrochloric Acid SCHEMBL27395505 | 0.87 | TACR1 (0.43) | TACR1NR3C1CYP19A1HTR1AHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088917-A | Substituted benzylamino nitrogen-containing non-aromatic heterocyclic compounds | PFIZER (US) | 1994-07-06 | — | — | CN | claimed |