Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.47 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | WIZ | O95785 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30961229 | 1.00 | CRBN (0.47) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL30942303 | 0.94 | IKZF2 (0.49) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL27301638 | 0.94 | IKZF2 (0.49) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL29648391 | 0.92 | IKZF2 (0.52) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL20442592 | 0.92 | IKZF2 (0.52) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL27302563 | 0.92 | IKZF2 (0.52) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL31726811 | 0.92 | CRBN (0.52) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL22498388 | 0.92 | CRBN (0.52) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL30942283 | 0.91 | IKZF2 (0.53) | CRBNIKZF2DDB1CSNK1A1WIZ | |
| SCHEMBL27302562 | 0.91 | IKZF2 (0.53) | CRBNIKZF2DDB1CSNK1A1WIZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | TIGER BIOTHERAPEUTICS INC. | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217972-A1 | GLUTARIMIDE-CONTAINING PAN-KRAS-MUTANT DEGRADER COMPOUNDS AND USES THEREOF | KRAS, VHL, HRAS | CRBN 298/4885IKZF2 2350/4885DDB1 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.