SCHEMBL27424201

SCHEMBL27424201

Cc1cccc(C(=O)OC(=O)c2ccc(C(=O)O)cc2)c1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
LMNA P02545 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
AKR1B10 O60218 1/20 0.43
TRPA1 O75762 1/20 0.43
ABCB11 O95342 1/20 0.43
DHFR P00374 1/20 0.43
MPO P05164 1/20 0.43
CYP1A2 P05177 1/20 0.43
CHRM1 P11229 1/20 0.43
AKR1B1 P15121 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
AKR1C3 P42330 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6113332 0.90 KMT2A (0.50) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL27813972 0.89 TSHR (0.42) ALDH1A1KDM4EHPGDHSD17B10AKR1C3
SCHEMBL28398675 0.87 NPC1 (0.50) KMT2AMEN1ALDH1A1HPGDAKR1C3
SCHEMBL6113326 0.86 MEN1 (0.50) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL32667968 0.86 MEN1 (0.50) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL30929009 0.81 KMT2A (0.50) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL108624 0.81 TSHR (0.52) ALDH1A1HPGDHSD17B10LMNACYP2C9
SCHEMBL29062652 0.80 AKR1C3 (0.53) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL7893551 0.78 HSD17B10 (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD
SCHEMBL30426368 0.78 HSD17B10 (0.47) KMT2AMEN1ALDH1A1KDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1129002-A Reduced fluorescence polymer compositions containing naphthoic acid EASTMAN CHEM CO (US) 1996-08-14 CN disclosed