Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27586073 | 0.92 | HPRT1 (0.52) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| Thioxanthene SCHEMBL27964760 | 0.91 | HPRT1 (0.39) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| Phenanthrene SCHEMBL27372954 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| Chrysene SCHEMBL27616409 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| SCHEMBL27740850 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2089665 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| SCHEMBL30928215 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| SCHEMBL28077721 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| SCHEMBL21176632 | 0.90 | HPRT1 (0.54) | HPRT1KIF11ALDH1A1MAPTCYP1A2 | |
| Water SCHEMBL28388195 | 0.89 | HPRT1 (0.52) | HPRT1KIF11ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736569-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligase | UNIV YALE | 2015-06-24 | — | — | CN | claimed |
| CN-108463463-A | Compound, preparation method and its medical usage of antagonism A3 adenosine receptors | 韩德株式会社 | 2018-08-28 | — | — | CN | disclosed |
| CN-108366992-A | Proteolysis targets chimera compound and its methods for making and using same | 耶鲁大学 | 2018-08-03 | — | — | CN | disclosed |
| CN-104736569-A | Compounds and methods for enhancing degradation of target proteins and other polypeptides by E3 ubiquitin ligase | UNIV YALE | 2015-06-24 | — | — | CN | disclosed |
| CN-1630646-A | Optically active azole derivative and process for producing the same | MITSUI CHEMICALS INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| CN-1109880-A | 3-(2-aminoethyl)-4-[3-(trifluoromethyl) benzoyl]-3,4-dihydro-1,4-benzoxazine derivative and preparation of same | SYNTHELABO (FR) | 1995-10-11 | — | — | CN | disclosed |