Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16350242 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL10215588 | 0.77 | HSD17B10 (0.40) | CNR2HSD17B10ATM | |
| SCHEMBL4721124 | 0.74 | SMN1; SMN2 (0.36) | MMP2ANPEPATMPOLB | |
| SCHEMBL606217 | 0.71 | F2 (0.44) | — | |
| SCHEMBL608859 | 0.71 | F2 (0.44) | — | |
| SCHEMBL642427 | 0.71 | F2 (0.44) | — | |
| SCHEMBL14843311 | 0.70 | CNR2 (0.32) | CNR2 | |
| SCHEMBL17327535 | 0.69 | CHRM2 (0.42) | — | |
| SCHEMBL642472 | 0.69 | CHRM2 (0.42) | — | |
| SCHEMBL10865220 | 0.69 | ACE (0.40) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137813-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |