SCHEMBL27428890

SCHEMBL27428890

[LiH].c1ccc2c(c1)Cc1ccccc1C2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
MAOA P21397 2/20 0.53
MAOB P27338 1/20 0.53
DRD2 P14416 1/20 0.52
DRD1 P21728 1/20 0.52
DRD4 P21917 1/20 0.52
DRD5 P21918 1/20 0.52
DRD3 P35462 1/20 0.52
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
HTR2A P28223 5/20 0.48
CYP2A6 P11509 1/20 0.48
TSHR P16473 2/20 0.47
CYP3A4 P08684 1/20 0.45
HTR2C P28335 2/20 0.42
HRH1 P35367 1/20 0.42
TRPA1 O75762 1/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22081972 0.96 CYP1A2 (0.62) CYP1A2MAOAMAOBDRD2DRD1
SCHEMBL1525601 0.96
SCHEMBL109650 0.96 CYP1A2 (0.62) CYP1A2MAOAMAOBDRD2DRD1
SCHEMBL29881712 0.96
Ammonia Solution, Strong SCHEMBL656057 0.92
Hydrochloric Acid SCHEMBL4314909 0.92
Benzene SCHEMBL19894402 0.92 CYP1A2 (0.59) CYP1A2MAOAMAOBDRD2DRD1
SCHEMBL7913483 0.92 CYP1A2 (0.59) CYP1A2MAOAMAOBDRD2DRD1
Bromide SCHEMBL2085597 0.92
Water SCHEMBL2528680 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1086522-A The preparation method of epoxy-terminated polymers EASTMAN KODAK CO (US) 1994-05-11 CN disclosed